Where it genuinely earns its keep
Strip plastic out of a hospital and medicine reverts a century. Sterile, single-use syringes, IV bags, blood bags, and tubing exist because plastic can be made cheaply, sterilized reliably, and thrown away without the cross-contamination risk of reusable glass and metal. The same is true for lightweight vehicle parts that cut fuel use, insulation that lowers a building's energy load, and prosthetics that would be heavier and pricier in almost any other material.
This is the part of plastic's story that's easy to lose in the backlash: in medicine, safety equipment, and a handful of engineering applications, it isn't a shortcut. It's the best tool available, and pretending otherwise doesn't help the argument for using less of it elsewhere.